2ZKD
Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (C, E) | DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3') | polymer | 12 | 3638.4 | 2 | hemi-methylated CpG DNA | ||
| 2 | B, D (D, F) | DNA (5'-D(*DGP*DCP*DAP*DAP*DTP*DCP*(5CM)P*DGP*DGP*DTP*DAP*DG)-3') | polymer | 12 | 3701.4 | 2 | hemi-methylated CpG DNA | ||
| 3 | E, F (A, B) | E3 ubiquitin-protein ligase UHRF1 | polymer | 210 | 23407.1 | 2 | UniProt (Q8VDF2) Pfam (PF02182) | Mus musculus (Mouse) | Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, Nuclear zinc finger protein Np95, Nuclear protein 95 |
| 4 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | I, J, K, L, M... (C, D, E, F, A...) | water | water | 18.0 | 663 | Chemie (HOH) |
Sequence modifications
A, B: 404 - 613 (UniProt: Q8VDF2)
| PDB | External Database | Details |
|---|---|---|
| Ser 404 | Lys 404 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 61493.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 121.1 | |
| All* | Total formula weight | 61615.0 |
