2ZK2
Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with glutathion conjugated 15-deoxy-delta12,14-prostaglandin J2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32530.7 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | C (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 3 | D (A) | (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid | non-polymer | 316.4 | 1 | Chemie (PTG) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 476 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 191 | - | expression tag |
| Ser 192 | - | expression tag |
| His 193 | - | expression tag |
| Met 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65061.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 623.8 | |
| All* | Total formula weight | 65685.1 |
