2ZI5
C4S dCK variant of dCK in complex with L-dA+UDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Deoxycytidine kinase | polymer | 279 | 32572.5 | 4 | UniProt (P27707) Pfam (PF01712) In PDB | Homo sapiens (human) | dCK |
2 | A, B, C, D | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
3 | A, B, C, D | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol | non-polymer | 251.2 | 4 | Chemie (3L1) | |||
4 | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1001 - 1260 (UniProt: P27707)
PDB | External Database | Details |
---|---|---|
Met 982 | - | expression tag |
Gly 983 | - | expression tag |
Ser 984 | - | expression tag |
Ser 985 | - | expression tag |
His 986 | - | expression tag |
His 987 | - | expression tag |
His 988 | - | expression tag |
His 989 | - | expression tag |
His 990 | - | expression tag |
His 991 | - | expression tag |
Ser 992 | - | expression tag |
Gly 993 | - | expression tag |
Leu 994 | - | expression tag |
Val 995 | - | expression tag |
Pro 996 | - | expression tag |
Arg 997 | - | expression tag |
Gly 998 | - | expression tag |
Ser 999 | - | expression tag |
His 1000 | - | expression tag |
Ser 1009 | Cys 9 | engineered mutation |
Ser 1045 | Cys 45 | engineered mutation |
Ser 1059 | Cys 59 | engineered mutation |
Ser 1146 | Cys 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130290.0 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2621.6 | |
All* | Total formula weight | 132911.7 |