2ZHV
Crystal structure of BACE1 at pH 7.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-secretase 1 | polymer | 411 | 45900.5 | 1 | UniProt (P56817) Pfam (PF00026) | Homo sapiens (human) | Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2, BACE1 |
| 2 | B (A) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A: -16 - 393 (UniProt: P56817)
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45900.5 | |
| All* | Total formula weight | 45900.5 |
