2ZEJ

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Leucine-rich repeat kinase 2	polymer	184	21421.7	2	UniProt (Q17RV3) Pfam (PF08477) UniProt (by SIFTS) (Q5S007)	Homo sapiens (human)	Dardarin
2	C, E (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, F (A, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
4	G, H (A, B)	water	water		18.0	112	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42843.5
Non-Polymers*	Number of molecules	4
	Total formula weight	935.0
All*	Total formula weight	43778.5

*Water molecules are not included.