2ZDU
Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 10 | polymer | 364 | 42059.7 | 1 | UniProt (P53779) Pfam (PF00069) | Homo sapiens (human) | Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | B (A) | 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid | non-polymer | 563.4 | 1 | Chemie (446) | |||
| 3 | C (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42059.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 563.4 | |
| All* | Total formula weight | 42623.1 |
