2ZDT
Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 10 | polymer | 364 | 42059.7 | 1 | UniProt (P53779) Pfam (PF00069) In PDB | Homo sapiens (human) | Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | A | 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1H)-yl)methyl]benzoic acid | non-polymer | 445.9 | 1 | Chemie (46C) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42059.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 538.0 | |
| All* | Total formula weight | 42597.7 |
