2ZC6
Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Penicillin-binding protein 1A | polymer | 24 | 2639.9 | 2 | UniProt (Q8DR59) | Streptococcus pneumoniae | PBP-1A, Exported protein 2 |
| 2 | B, D (B, D) | Penicillin-binding protein 1A | polymer | 390 | 43566.0 | 2 | UniProt (Q549Y6) Pfam (PF00905) UniProt (by SIFTS) (Q04707) | Streptococcus pneumoniae | |
| 3 | E, F, G, H, J... (B, D) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | I, N (B, D) | (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 385.5 | 2 | Chemie (TEB) | |||
| 5 | O, P (B, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
B, D: 264 - 653 (UniProt: Q549Y6)
| PDB | External Database | Details |
|---|---|---|
| Gln 545 | Arg 545 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92411.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1294.3 | |
| All* | Total formula weight | 93706.1 |
