2ZB7
Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADPH and nicotinamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Prostaglandin reductase 2 | polymer | 357 | 38961.3 | 1 | UniProt (Q8N8N7) Pfam (PF16884) Pfam (PF00107) In PDB | Homo sapiens (Human) | PTGR2, 15-oxoprostaglandin 13-reductase, Zinc-binding alcohol dehydrogenase domain-containing protein 1 |
| 2 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | A | NICOTINAMIDE | non-polymer | 122.1 | 1 | Chemie (NCA) | |||
| 4 | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence modifications
A: 1 - 351 (UniProt: Q8N8N7)
| PDB | External Database | Details |
|---|---|---|
| Ala -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38961.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 867.5 | |
| All* | Total formula weight | 39828.8 |
