2ZA5

Crystal Structure of human tryptase with potent non-peptide inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tryptase beta 2	polymer	245	27491.4	4	UniProt (Q6B052) Pfam (PF00089) UniProt (by SIFTS) (P20231)	Homo sapiens (human)
2	E, F, G, H (A, B, C, D)	(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone	non-polymer		412.5	4	Chemie (2FF)
3	I, J, K, L (A, B, C, D)	water	water		18.0	431	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	109965.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1649.9
All*	Total formula weight	111615.6

*Water molecules are not included.