2Z7S
Crystal Structure of the N-terminal Kinase Domain of Human RSK1 bound to Purvalnol A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribosomal protein S6 kinase alpha-1 | polymer | 321 | 36777.4 | 1 | UniProt (Q15418) Pfam (PF00069) | Homo sapiens (human) | S6K-alpha 1, 90 kDa ribosomal protein S6 kinase 1, p90-RSK 1, Ribosomal S6 kinase 1, RSK-1, pp90RSK1, p90S6K, MAP kinase-activated protein kinase 1a, MAPKAPK1A |
| 2 | B (A) | 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL | non-polymer | 388.9 | 1 | Chemie (P01) | |||
| 3 | C (A) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36777.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 388.9 | |
| All* | Total formula weight | 37166.3 |
