2Z7H
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-210
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Geranylgeranyl pyrophosphate synthetase | polymer | 340 | 39299.1 | 2 | UniProt (Q12051) Pfam (PF00348) | Saccharomyces cerevisiae (baker's yeast) | GGPP synthetase, GGPPSase, Geranylgeranyl diphosphate synthase, BET2 suppressor protein 1 |
| 2 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | D, E (A, B) | {1-HYDROXY-3-[METHYL(4-PHENYLBUTYL)AMINO]PROPANE-1,1-DIYL}BIS(PHOSPHONIC ACID) | non-polymer | 381.3 | 2 | Chemie (GG3) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 632 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 340 (UniProt: Q12051)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Thr 2 | - | expression tag |
| Lys 3 | - | expression tag |
| Asn 4 | - | expression tag |
| Lys 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78598.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 786.9 | |
| All* | Total formula weight | 79385.0 |
