2Z5Y
Crystal Structure of Human Monoamine Oxidase A (G110A) with Harmine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Amine oxidase [flavin-containing] A | polymer | 513 | 58271.9 | 1 | UniProt (P21397) Pfam (PF01593) | Homo sapiens (human) | Monoamine oxidase type A, MAO-A |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | non-polymer | 212.2 | 1 | Chemie (HRM) | |||
| 4 | D, E (A) | DECYL(DIMETHYL)PHOSPHINE OXIDE | non-polymer | 218.3 | 2 | Chemie (DCX) | |||
| 5 | F (A) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A: 12 - 524 (UniProt: P21397)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Gly 110 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58271.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1434.4 | |
| All* | Total formula weight | 59706.3 |






