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2Z32

Crystal structure of Keap1 complexed with Prothymosin alpha

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kelch-like ECH-associated protein 1polymer31835006.31UniProt (Q9Z2X8)
Pfam (PF01344)
Mus musculus (house mouse)Cytosolic inhibitor of Nrf2, INrf2, Keap1
2B
(B)
Prothymosin alphapolymer161790.71UniProt (P26350)
3C, D, E, F, G
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
4H, I
(A, B)
waterwater18.0250Chemie (HOH)
Sequence modifications
A: 309 - 624 (UniProt: Q9Z2X8)
PDBExternal DatabaseDetails
Met 308-initiating methionine
Tyr 625-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36796.9
Non-Polymers*Number of molecules5
Total formula weight480.3
All*Total formula weight37277.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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