2YU1
Crystal structure of hJHDM1A complexed with a-ketoglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | JmjC domain-containing histone demethylation protein 1A | polymer | 451 | 52913.8 | 1 | UniProt (Q9Y2K7) Pfam (PF17811) In PDB | Homo sapiens (human) | [Histone-H3]-lysine-36 demethylase 1A, F-box/LRR- repeat protein 11, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina |
| 2 | A | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | A | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 4 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 1 - 383 (UniProt: Q9Y2K7)
| PDB | External Database | Details |
|---|---|---|
| Ser 252 | Lys 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52913.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 201.9 | |
| All* | Total formula weight | 53115.7 |
