2YU1
Crystal structure of hJHDM1A complexed with a-ketoglutarate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 A 600 |
| Chain | Residue |
| A | HIS212 |
| A | ASP214 |
| A | HIS284 |
| A | AKG701 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE AKG A 701 |
| Chain | Residue |
| A | TYR222 |
| A | LYS229 |
| A | HIS284 |
| A | VAL286 |
| A | FE2600 |
| A | HOH705 |
| A | HOH722 |
| A | HOH754 |
| A | ASN142 |
| A | ILE144 |
| A | THR209 |
| A | HIS212 |
| A | ASP214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | THR209 | |
| A | LYS229 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:16362057, ECO:0007744|PDB:2YU1, ECO:0007744|PDB:2YU2 |
| Chain | Residue | Details |
| A | HIS212 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|Ref.27, ECO:0007744|PDB:2YU1, ECO:0007744|PDB:2YU2 |
| Chain | Residue | Details |
| A | ASP214 | |
| A | HIS284 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER28 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | PHE456 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | GLY460 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS505 |
