2YU1
Crystal structure of hJHDM1A complexed with a-ketoglutarate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 A 600 |
| Chain | Residue |
| A | HIS212 |
| A | ASP214 |
| A | HIS284 |
| A | AKG701 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE AKG A 701 |
| Chain | Residue |
| A | TYR222 |
| A | LYS229 |
| A | HIS284 |
| A | VAL286 |
| A | FE2600 |
| A | HOH705 |
| A | HOH722 |
| A | HOH754 |
| A | ASN142 |
| A | ILE144 |
| A | THR209 |
| A | HIS212 |
| A | ASP214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16362057","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2YU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YU2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2007","submissionDatabase":"PDB data bank","title":"Structural basis for histone demethylation by JHDM1.","authors":["Han Z.","Liu P.","Gu L.","Zhang Y.","Li H.","Chen S.","Chai J."]}},{"source":"PDB","id":"2YU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YU2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
