2YQ6
Structure of Bcl-xL bound to BimSAHB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | BCL-2-LIKE PROTEIN 1 | polymer | 158 | 17918.0 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | HOMO SAPIENS (HUMAN) | BCL-XL, BCL2-L-1, APOPTOSIS REGULATOR BCL-X |
| 2 | B | BIM BETA 5 | polymer | 19 | 2183.5 | 1 | UniProt (O43521) Pfam (PF08945) In PDB | HOMO SAPIENS | BIM |
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 1 - 26 (UniProt: Q07817)
B: 147 - 164 (UniProt: O43521)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Mk8 154 | Arg 21 | engineered mutation |
| Mk8 158 | Glu 25 | engineered mutation |
| Nh2 165 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20101.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 644.7 | |
| All* | Total formula weight | 20746.1 |
