2YPE
Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3'- cyclic AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE | polymer | 221 | 24242.9 | 1 | UniProt (P16330) Pfam (PF05881) | MUS MUSCULUS (HOUSE MOUSE) | CNP, CNPASE |
| 2 | B, D (A) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E (A) | 2',3'- cyclic AMP | non-polymer | 329.2 | 1 | Chemie (ACK) | |||
| 5 | F (A) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A: 159 - 378 (UniProt: P16330)
| PDB | External Database | Details |
|---|---|---|
| Gly 158 | - | expression tag |
| Ser 309 | His 309 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24242.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 484.8 | |
| All* | Total formula weight | 24727.6 |
