2YL5
Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | BETA-N-ACETYLHEXOSAMINIDASE | polymer | 442 | 49633.7 | 4 | UniProt (P49610) Pfam (PF00728) | STREPTOCOCCUS PNEUMONIAE | GLYCOSIDE HYDROLASE |
| 2 | E, F, G, H, I... (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) | |||
| 3 | J, K, L, O, S... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 4 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 2317 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 627 - 1064 (UniProt: P49610)
| PDB | External Database | Details |
|---|---|---|
| Gly 623 | - | expression tag |
| Ser 624 | - | expression tag |
| His 625 | - | expression tag |
| Met 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198535.0 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 987.9 | |
| All* | Total formula weight | 199522.8 |
