2YKO

Structure of the human LINE-1 ORF1p trimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	LINE-1 ORF1P	polymer	233	28023.4	3	UniProt (Q15605) Pfam (PF17489) Pfam (PF02994) Pfam (PF17490) UniProt (by SIFTS) (Q9UN81) In PDB	HOMO SAPIENS (HUMAN)	ORF1 CODES FOR A 40 KDA PRODUCT
2	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3		water	water		18.0	190	Chemie (HOH)

Sequence modifications

A, B, C: 104 - 330 (UniProt: Q15605)

PDB	External Database	Details
Mse 104	Cys 104	engineered mutation
Ala 105	Arg 105	engineered mutation
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
Ala 121	Met 121	engineered mutation
Ile 125	Met 125	engineered mutation
Ile 128	Met 128	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	84070.2
Non-Polymers*	Number of molecules	2
	Total formula weight	70.9
All*	Total formula weight	84141.1

*Water molecules are not included.