2YKB
Tricyclic series of Hsp90 inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HEAT SHOCK PROTEIN HSP 90-ALPHA | polymer | 209 | 23361.5 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HEAT SHOCK 86 KDA, HSP 86, HSP86, RENAL CARCINOMA ANTIGEN NY-REN-38, HSP90 |
2 | A | N-[4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL]-SUCCINAMIDE | non-polymer | 397.4 | 1 | Chemie (YKB) | |||
3 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 18 - 223 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Gly 15 | - | expression tag |
His 16 | - | expression tag |
Met 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23361.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 397.4 | |
All* | Total formula weight | 23758.9 |