2YK4
Structure of Neisseria LOS-specific sialyltransferase (NST).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE | polymer | 327 | 38210.2 | 1 | UniProt (P72097) Pfam (PF07922) | NEISSERIA MENINGITIDIS SEROGROUP B | ALPHA 2\,3-ST, BETA-GALACTOSIDE ALPHA-2\,3-SIALYL TRANSFERASE, LIPOOLIGOSACCHARIDE SIALYLTRANSFERASE, LOS-SPECIFIC SIALYLTRANSFERASE |
| 2 | B (A) | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL | non-polymer | 602.8 | 1 | Chemie (EGC) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A: 49 - 370 (UniProt: P72097)
| PDB | External Database | Details |
|---|---|---|
| Glu 48 | - | expression tag |
| Leu 371 | - | expression tag |
| Val 372 | - | expression tag |
| Pro 373 | - | expression tag |
| Arg 374 | - | expression tag |
| Trp 102 | Arg 102 | variant |
| Ala 129 | Ser 129 | variant |
| Ile 168 | Gly 168 | variant |
| Ala 242 | Thr 242 | variant |
| Asn 273 | Lys 273 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38210.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 885.1 | |
| All* | Total formula weight | 39095.2 |
