2YK4
Structure of Neisseria LOS-specific sialyltransferase (NST).
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE EGC A 1374 |
| Chain | Residue |
| A | PHE54 |
| A | LEU143 |
| A | VAL146 |
| A | SER147 |
| A | ILE148 |
| A | ALA150 |
| A | PHE151 |
| A | HOH2062 |
| A | HOH2092 |
| A | HOH2252 |
| A | TYR56 |
| A | VAL79 |
| A | TRP102 |
| A | PHE106 |
| A | TYR110 |
| A | LEU112 |
| A | ASN113 |
| A | SER115 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1375 |
| Chain | Residue |
| A | LEU59 |
| A | VAL63 |
| A | ASP164 |
| A | GLY166 |
| A | ILE214 |
| A | HOH2106 |
| A | HOH2107 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1376 |
| Chain | Residue |
| A | SER322 |
| A | GLY323 |
| A | HOH2072 |
| A | HOH2108 |
| A | HOH2221 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1377 |
| Chain | Residue |
| A | ALA69 |
| A | GLN70 |
| A | ASN271 |
| A | THR366 |
| A | PHE367 |
| A | ASP368 |
| A | HOH2009 |
| A | HOH2253 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1378 |
| Chain | Residue |
| A | HIS71 |
| A | GLU74 |
| A | ARG137 |
| A | ARG251 |
| A | ASN273 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21880735","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"21880735","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21880735","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2YK7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
