2YIX
Triazolopyridine Inhibitors of p38
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MITOGEN-ACTIVATED PROTEIN KINASE 14 | polymer | 351 | 40263.0 | 1 | UniProt (Q16539) Pfam (PF00069) | HOMO SAPIENS | P38 KINASE, MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, CSAID-BINDING PROTEIN, CSBP, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38 ALPHA, SAPK2A |
| 2 | B (A) | 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea | non-polymer | 369.5 | 1 | Chemie (YIX) | |||
| 3 | C (A) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40263.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 369.5 | |
| All* | Total formula weight | 40632.5 |
