2YIW
triazolopyridine inhibitors of p38 kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MITOGEN-ACTIVATED PROTEIN KINASE 14 | polymer | 359 | 41212.0 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, CSAID-BINDING PROTEIN, CSBP, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, P38 KINASE, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38 ALPHA, SAPK2A |
| 2 | A | 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea | non-polymer | 539.7 | 1 | Chemie (YIW) | |||
| 3 | A | 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine | non-polymer | 257.2 | 1 | Chemie (I46) | |||
| 4 | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41212.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 796.9 | |
| All* | Total formula weight | 42008.9 |
