2YIN

STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DEDICATOR OF CYTOKINESIS PROTEIN 2	polymer	436	51650.7	2	UniProt (Q92608) Pfam (PF06920) Pfam (PF20422) Pfam (PF20421)	HOMO SAPIENS (HUMAN)	DOCK2
2	C, D (C, D)	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1	polymer	196	21861.2	2	UniProt (P63000) Pfam (PF00071)	HOMO SAPIENS (HUMAN)	RAC1, CELL MIGRATION-INDUCING GENE 5 PROTEIN, RAS-LIKE PROTEIN TC25, P21-RAC1
3	E, F, G, H (A, B, C, D)	water	water		18.0	91	Chemie (HOH)

Sequence modifications

A, B: 1192 - 1622 (UniProt: Q92608)

PDB	External Database	Details
Gly 1187	-	expression tag
Glu 1188	-	expression tag
Cys 1189	-	expression tag
Gly 1190	-	expression tag
Asp 1191	-	expression tag

C, D: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Met -18	-	expression tag
Ala -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Leu -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	147023.6
All*	Total formula weight	147023.6

*Water molecules are not included.