2YGW
Crystal structure of human MCD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL | polymer | 460 | 51429.8 | 2 | UniProt (O95822) Pfam (PF17408) Pfam (PF05292) | HOMO SAPIENS (HUMAN) | |
| 2 | C, D (A, B) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 3 | E (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 490 (UniProt: O95822)
| PDB | External Database | Details |
|---|---|---|
| Gly -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ala 58 | Glu 58 | engineered mutation |
| Ala 59 | Lys 59 | engineered mutation |
| Ala 278 | Glu 278 | engineered mutation |
| Ala 279 | Glu 279 | engineered mutation |
| Ala 280 | Lys 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 102859.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 102921.6 |
