2YER
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE CHK1 | polymer | 276 | 31840.7 | 1 | UniProt (O14757) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | CHK1 CHECKPOINT KINASE |
| 2 | B (A) | 5-(HYDROXYMETHYL)-8-(1H-PYRROL-2-YL)-2H-[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-ONE | non-polymer | 280.3 | 1 | Chemie (TQ1) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E, F, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | J (A) | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31840.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 748.8 | |
| All* | Total formula weight | 32589.5 |
