2YDV
Thermostabilised HUMAN A2a Receptor with NECA bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ADENOSINE RECEPTOR A2A | polymer | 325 | 36022.8 | 1 | UniProt (P29274) Pfam (PF00001) In PDB | HOMO SAPIENS (HUMAN) | THERMOSTABILISED HUMAN A2A RECEPTOR |
2 | A | N-ETHYL-5'-CARBOXAMIDO ADENOSINE | non-polymer | 308.3 | 1 | Chemie (NEC) | |||
3 | A | octyl 1-thio-beta-D-glucopyranoside | non-polymer | 308.4 | 5 | Chemie (SOG) | |||
4 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 1 - 317 (UniProt: P29274)
PDB | External Database | Details |
---|---|---|
Ala 48 | Leu 48 | engineered mutation |
Leu 54 | Ala 54 | engineered mutation |
Ala 65 | Thr 65 | engineered mutation |
Ala 89 | Gln 89 | engineered mutation |
Ala 154 | Asn 154 | engineered mutation |
Ala 318 | - | expression tag |
Ala 319 | - | expression tag |
Glu 320 | - | expression tag |
Asn 321 | - | expression tag |
Leu 322 | - | expression tag |
Tyr 323 | - | expression tag |
Phe 324 | - | expression tag |
Gln 325 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36022.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1850.5 | |
All* | Total formula weight | 37873.2 |