2YDP
Structure of the E242A mutant of the alpha-l-arabinofuranosidase arb93a from fusarium graminearum in complex with an iminosugar inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | EXO-1,5-ALPHA-L-ARABINOFURANOBIOSIDASE | polymer | 367 | 41063.3 | 3 | UniProt (B8ZY56) | GIBBERELLA ZEAE | ALPHA-L-ARABINOFURANOSIDASE |
| 2 | D, G, J (A, B, C) | 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL | non-polymer | 133.1 | 3 | Chemie (EDG) | |||
| 3 | E, H, K (A, B, C) | alpha-L-arabinofuranose | non-polymer | 150.1 | 3 | Chemie (AHR) | |||
| 4 | F, I, L (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | M, N, O (A, B, C) | water | water | 18.0 | 964 | Chemie (HOH) |
Sequence modifications
A, B, C: 17 - 381 (UniProt: B8ZY56)
| PDB | External Database | Details |
|---|---|---|
| Ala 15 | - | expression tag |
| Met 16 | - | expression tag |
| Ala 242 | Glu 226 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123190.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 970.1 | |
| All* | Total formula weight | 124160.0 |
