2YCF
Crystal Structure of Checkpoint Kinase 2 in complex with Inhibitor PV1531
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE CHK2 | polymer | 322 | 36433.1 | 1 | UniProt (O96017) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 2, CDS1 |
| 2 | B (A) | (2E)-N-hydroxy-2-[1-(4-{[(4-{(1E)-1-[2-(N'-hydroxycarbamimidoyl)hydrazinylidene]ethyl}phenyl)carbamoyl]amino}phenyl)ethylidene]hydrazinecarboximidamide | non-polymer | 440.5 | 1 | Chemie (YCF) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | E (A) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A: 210 - 530 (UniProt: O96017)
| PDB | External Database | Details |
|---|---|---|
| Met 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36433.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 526.8 | |
| All* | Total formula weight | 36959.9 |
