2YCE

Structure of an Archaeal fructose-1,6-bisphosphate aldolase with the catalytic Lys covalently bound to the carbinolamine intermediate of the substrate.

Replaces:  1W8R

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1	polymer	263	28741.1	10	UniProt (P58315) Pfam (PF01791)	THERMOPROTEUS TENAX	FRUCTOSE-BIPHOSPHATE ALDOLASE CLASS I, FBP ALDOLASE
2	K, L, M, N, O... (A, B, C, D, E...)	D-MANNITOL-1,6-DIPHOSPHATE	non-polymer		342.1	10	Chemie (M2P) PubChem (23644175) PubChem (44448097) PubChem (449501) PubChem (4369446) PubChem (5288174)
3	AA, BA, CA, DA, U... (G, H, I, J, A...)	water	water		18.0	1518	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 263 (UniProt: P58315)

PDB	External Database	Details
Phe 146	Tyr 146	engineered mutation
Ser 173	Ala 173	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	287410.6
Non-Polymers*	Number of molecules	10
	Total formula weight	3421.3
All*	Total formula weight	290832.0

*Water molecules are not included.