2YC0
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLUTARATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR | polymer | 352 | 40610.6 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | HOMO SAPIENS (HUMAN) | FACTOR INHIBITING HIF-1, FIH-1, HYPOXIA-INDUCIBLE FACTOR ASPARAGINE HYDROXYLASE |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C (A) | (2R)-2-hydroxypentanedioic acid | non-polymer | 148.1 | 1 | Chemie (2HG) | |||
| 4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | K (A) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40610.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 864.5 | |
| All* | Total formula weight | 41475.0 |
