2YBX

Crystal Structure of Human Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE-2 ALPHA	polymer	394	45313.0	2	UniProt (P48426) Pfam (PF01504)	HOMO SAPIENS (HUMAN)	1-PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE 2-ALPHA, DIPHOSPHOINOSITIDE KINASE 2-ALPHA, PIP5KIII, PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE II ALPHA, PI(5)P 4-KINASE TYPE II ALPHA, PIP4KII-ALPHA, PTDINS(4)P-5-KINASE B ISOFORM, PTDINS(4)P-5-KINASE C ISOFORM, PTDINS(5)P-4-KINASE ISOFORM 2-ALPHA
2	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	D, E (A, B)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B: 35 - 405 (UniProt: P48426)

PDB	External Database	Details
Met 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
Ser 19	-	expression tag
Ser 20	-	expression tag
Gly 21	-	expression tag
Val 22	-	expression tag
Asp 23	-	expression tag
Leu 24	-	expression tag
Gly 25	-	expression tag
Thr 26	-	expression tag
Glu 27	-	expression tag
Asn 28	-	expression tag
Leu 29	-	expression tag
Tyr 30	-	expression tag
Phe 31	-	expression tag
Gln 32	-	expression tag
Ser 33	-	expression tag
Met 34	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90626.0
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	90720.9

*Water molecules are not included.