2YBS
JMJD2A COMPLEXED WITH S-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | LYSINE-SPECIFIC DEMETHYLASE 4A | polymer | 381 | 44326.3 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) In PDB | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A |
2 | C, D | HISTONE H3.1T | polymer | 12 | 1356.6 | 2 | UniProt (Q16695) In PDB | HOMO SAPIENS | H3/T, H3T, H3/G |
3 | A, B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | A, B | (2S)-2-HYDROXYPENTANEDIOIC ACID | non-polymer | 148.1 | 2 | Chemie (S2G) | |||
7 | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 359 (UniProt: O75164)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
Ser -14 | - | expression tag |
Ser -13 | - | expression tag |
Gly -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Leu -9 | - | expression tag |
Gly -8 | - | expression tag |
Thr -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 91365.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 636.5 | |
All* | Total formula weight | 92002.3 |