2YAZ
The Crystal Structure of Leishmania major dUTPase in complex dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | DUTPASE | polymer | 271 | 30609.8 | 4 | UniProt (O15826) Pfam (PF08761) | LEISHMANIA MAJOR | DEOXYURIDINE TRIPHOSPHATASE (DUTP DIPHOSPHATASE), DEOXYURIDINE TRIPHOSPHATE NUCLEOTIDOHYDROLASE |
| 2 | E, I, J, N (A, B, D, E) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 4 | Chemie (UMP) | |||
| 3 | F, H, L, M (A, D, E) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G, K, O (A, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | P, Q, R, S (A, B, D, E) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 1 - 268 (UniProt: O15826)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 122439.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1689.9 | |
| All* | Total formula weight | 124129.3 |
