2Y8S

Co-structure of an AMA1 mutant (Y230A) with a surface exposed region of RON2 from Toxoplasma gondii

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	APICAL MEMBRANE ANTIGEN, PUTATIVE	polymer	432	47921.4	2	UniProt (B9QC59) Pfam (PF02430) UniProt (by SIFTS) (B6KAM0) In PDB	TOXOPLASMA GONDII	AMA1, APICAL MEMBRANE ANTIGEN 1
2	B, E	RHOPTRY NECK PROTEIN 2	polymer	37	3753.3	2	UniProt (B9QQC1) UniProt (by SIFTS) (B6KV60) In PDB	TOXOPLASMA GONDII	RON2
3	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A	BORIC ACID	non-polymer		61.8	2	Chemie (BO3)
5	A, D	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6		water	water		18.0	211	Chemie (HOH)

Sequence modifications

A, D: 64 - 484 (UniProt: B9QC59)

PDB	External Database	Details
Gly 59	-	expression tag
Ser 60	-	expression tag
Ala 61	-	expression tag
Met 62	-	expression tag
Gly 63	-	expression tag
Ala 485	-	expression tag
Ala 486	-	expression tag
Leu 487	-	expression tag
Val 488	-	expression tag
Pro 489	-	expression tag
Arg 490	-	expression tag
Ala 230	Tyr 230	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	103349.3
Non-Polymers*	Number of molecules	7
	Total formula weight	842.4
All*	Total formula weight	104191.7

*Water molecules are not included.