2Y88
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE (VARIANT D11N) WITH BOUND PRFAR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHORIBOSYL ISOMERASE A | polymer | 244 | 25657.8 | 1 | UniProt (P60578) Pfam (PF00977) UniProt (by SIFTS) (P9WMM5) | MYCOBACTERIUM TUBERCULOSIS | N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE, 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE, PRAI |
| 2 | B (A) | [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | non-polymer | 577.3 | 1 | Chemie (2ER) | |||
| 3 | C (A) | water | water | 18.0 | 394 | Chemie (HOH) |
Sequence modifications
A: 2 - 245 (UniProt: P60578)
| PDB | External Database | Details |
|---|---|---|
| Asn 11 | Asp 10 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25657.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 577.3 | |
| All* | Total formula weight | 26235.1 |
