2Y6O
Crystal structure of EphA4 kinase domain in complex with Dasatinib.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EPHRIN TYPE-A RECEPTOR 4 | polymer | 291 | 32931.1 | 1 | UniProt (Q03137) Pfam (PF07714) | MUS MUSCULUS (HOUSE MOUSE) | EPHA4, TYROSINE-PROTEIN KINASE RECEPTOR MPK-3, TYROSINE-PROTEIN KINASE RECEPTOR SEK-1 |
| 2 | B (A) | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | non-polymer | 488.0 | 1 | Chemie (1N1) | |||
| 3 | C (A) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32931.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 488.0 | |
| All* | Total formula weight | 33419.1 |
