2Y3R

Structure of the tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P21 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TAML	polymer	530	58189.7	4	UniProt (D3Y1I2)	STREPTOMYCES SP. 307-9
2	E, J, P, W (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
3	F, Q (A, C)	TIRANDAMYCIN E	non-polymer		403.5	2	Chemie (TIR)
4	G, L, R, Y (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	AA, H, M, N, S... (D, A, B, C)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
6	BA, CA, I, O, U... (D, A, B, C)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
7	K, X (B, D)	TIRANDAMYCIN D	non-polymer		401.5	2	Chemie (TRK)
8	DA, EA, FA, GA (A, B, C, D)	water	water		18.0	2000	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 500 (UniProt: D3Y1I2)

PDB	External Database	Details
Met -29	-	expression tag
Gly -28	-	expression tag
Ser -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Asp -16	-	expression tag
Tyr -15	-	expression tag
Asp -14	-	expression tag
Ile -13	-	expression tag
Pro -12	-	expression tag
Thr -11	-	expression tag
Thr -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	232758.8
Non-Polymers*	Number of molecules	25
	Total formula weight	5706.6
All*	Total formula weight	238465.5

*Water molecules are not included.