2Y34
S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EGL NINE HOMOLOG 1 | polymer | 252 | 28125.9 | 1 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (Human) | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2, PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2, SM-20, HIF-PH2, HIF-PROLYL HYDROXYLASE 2, HPH-2, PHD2 |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C, D (A) | N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE | non-polymer | 280.7 | 2 | Chemie (UN9) | |||
| 4 | E (A) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 181 - 426 (UniProt: Q9GZT9)
| PDB | External Database | Details |
|---|---|---|
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
| His 177 | - | expression tag |
| Met 178 | - | expression tag |
| Ala 179 | - | expression tag |
| Ser 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28125.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 617.2 | |
| All* | Total formula weight | 28743.1 |
