2Y34

S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0031418	molecular_function	L-ascorbic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 A 501

Chain	Residue
A	HIS313
A	ASP315
A	HIS374
A	UN9601
A	HOH2073

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UN9 A 601

Chain	Residue
A	HIS313
A	ASP315
A	TYR329
A	LEU343
A	HIS374
A	VAL376
A	ARG383
A	ARG398
A	VAL401
A	FE2501
A	HOH2073
A	HOH2112
A	ASP254
A	MET299
A	TYR303
A	TYR310

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE UN9 A 602

Chain	Residue
A	TRP258
A	ASP320
A	ARG322
A	PHE391
A	VAL401
A	HOH2054
A	HOH2113

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16782814, ECO:0000269|PubMed:19604478, ECO:0000269|PubMed:28594552, ECO:0007744|PDB:2G19, ECO:0007744|PDB:3HQU, ECO:0007744|PDB:5V18

Chain	Residue	Details
A	HIS313
A	ASP315
A	HIS374

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:19604478

Chain	Residue	Details
A	ARG383

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:21601578

Chain	Residue	Details
A	CYS201
A	CYS208
A	SNC302
A	CYS323
A	CYS326

---