2Y21

The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291V mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	HAMP	polymer	56	6305.2	12	UniProt (O28769) Pfam (PF00672)	ARCHAEOGLOBUS FULGIDUS	AF1503
2	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	61	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 278 - 331 (UniProt: O28769)

PDB	External Database	Details
His 276	-	expression tag
Met 277	-	expression tag
Val 291	Ala 291	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	75663.0
All*	Total formula weight	75663.0

*Water molecules are not included.