2Y1Z
Human alphaB Crystallin ACD R120G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ALPHA-CRYSTALLIN B CHAIN | polymer | 94 | 10647.0 | 2 | UniProt (P02511) Pfam (PF00011) | HOMO SAPIENS (HUMAN) | ALPHAB-CRYSTALLIN, ALPHA(B)-CRYSTALLIN, HEAT SHOCK PROTEIN BETA-5, HSPB5, RENAL CARCINOMA ANTIGEN NY-REN-27, ROSENTHAL FIBER COMPONENT |
| 2 | C, E, F (A, B) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 3 | Chemie (MRD) | |||
| 3 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B: 67 - 157 (UniProt: P02511)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | - | expression tag |
| Ala 65 | - | expression tag |
| Met 66 | - | expression tag |
| Gly 120 | Arg 120 | engineered mutation |
| Met 137 | Leu 137 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21294.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 472.7 | |
| All* | Total formula weight | 21766.7 |
