2Y0N

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MSL3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MALE-SPECIFIC LETHAL 3 HOMOLOG	polymer	211	24776.7	4	UniProt (Q8N5Y2) Pfam (PF05712) In PDB	HOMO SAPIENS (HUMAN)	MALE-SPECIFIC LETHAL-3 HOMOLOG 1, MALE-SPECIFIC LETHAL-3 PROTEIN-LIKE 1, MSL3-LIKE 1, MSL3
2	E, F, G, H	MALE-SPECIFIC LETHAL 1 HOMOLOG	polymer	56	6271.1	4	UniProt (Q6PDM1) Pfam (PF15275) In PDB	MUS MUSCULUS (HOUSE MOUSE)	MSL-1, HAMPIN, MALE-SPECIFIC LETHAL 1-LIKE 1, MSL1-LIKE 1, MALE-SPECIFIC LETHAL-1 HOMOLOG 1, MSL1

Sequence modifications

A, B, C, D: 167 - 289 (UniProt: Q8N5Y2)

PDB	External Database	Details
Met 165	-	expression tag
Gly 166	-	expression tag

A, B, C, D: 442 - 518 (UniProt: Q8N5Y2)

PDB	External Database	Details
Tyr 290	-	insertion
Asp 291	-	insertion
Ile 292	-	insertion
Pro 293	-	insertion
Pro 294	-	insertion
Thr 295	-	insertion
Thr 296	-	insertion
Glu 440	-	insertion
Phe 441	-	insertion

E, F, G, H: 545 - 597 (UniProt: Q6PDM1)

PDB	External Database	Details
Gly 542	-	expression tag
Ala 543	-	expression tag
Met 544	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	124191.0
All*	Total formula weight	124191.0

*Water molecules are not included.