2Y03
TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND AGONIST ISOPRENALINE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BETA-1 ADRENERGIC RECEPTOR | polymer | 315 | 35940.8 | 2 | UniProt (P07700) Pfam (PF00001) | MELEAGRIS GALLOPAVO (TURKEY) | BETA-1 ADRENORECEPTOR, BETA-1 ADRENOCEPTOR, BETA-T |
| 2 | C, I (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 3 | D, E, F, J, K... (A, B) | HEGA-10 | non-polymer | 379.5 | 6 | Chemie (2CV) | |||
| 4 | G, M (A, B) | ISOPRENALINE | non-polymer | 211.3 | 2 | Chemie (5FW) | |||
| 5 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 368 (UniProt: P07700)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | expression tag |
| Gly 32 | - | expression tag |
| Ser 68 | Arg 68 | engineered mutation |
| Val 90 | Met 90 | engineered mutation |
| Leu 116 | Cys 116 | engineered mutation |
| Ala 227 | Tyr 227 | engineered mutation |
| - | Cys 244 | deletion |
| - | Glu 245 | deletion |
| - | Gly 246 | deletion |
| - | Arg 247 | deletion |
| - | Phe 248 | deletion |
| - | Tyr 249 | deletion |
| - | Gly 250 | deletion |
| - | Ser 251 | deletion |
| - | Gln 252 | deletion |
| - | Glu 253 | deletion |
| - | Gln 254 | deletion |
| - | Pro 255 | deletion |
| - | Gln 256 | deletion |
| - | Pro 257 | deletion |
| - | Pro 258 | deletion |
| - | Pro 259 | deletion |
| - | Leu 260 | deletion |
| - | Pro 261 | deletion |
| - | Gln 262 | deletion |
| - | His 263 | deletion |
| - | Gln 264 | deletion |
| - | Pro 265 | deletion |
| - | Ile 266 | deletion |
| - | Leu 267 | deletion |
| - | Gly 268 | deletion |
| - | Asn 269 | deletion |
| - | Gly 270 | deletion |
| - | Arg 271 | deletion |
| Leu 282 | Ala 282 | engineered mutation |
| Ala 327 | Phe 327 | engineered mutation |
| Met 338 | Phe 338 | engineered mutation |
| Ala 358 | Cys 358 | engineered mutation |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71881.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3695.9 | |
| All* | Total formula weight | 75577.4 |
