2XXV
Crystal structure of the GluK2 (GluR6) M770K LBD dimer in complex with kainate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 | polymer | 261 | 29623.9 | 2 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) In PDB | RATTUS NORVEGICUS (NORWAY RAT) | GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6 |
| 2 | A, B | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 2 | Chemie (KAI) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 501 | Chemie (HOH) |
Sequence modifications
A, B: 429 - 544 (UniProt: P42260)
A, B: 667 - 806 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 428 | - | expression tag |
| Pro 807 | - | expression tag |
| Arg 808 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 555 | - | linker |
| Thr 566 | - | linker |
| Lys 770 | Met 770 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59247.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 461.9 | |
| All* | Total formula weight | 59709.8 |
