2XXU

Crystal structure of the GluK2 (GluR6) M770K LBD dimer in complex with glutamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2	polymer	261	29623.9	2	UniProt (P42260) Pfam (PF10613) Pfam (PF00060) In PDB	RATTUS NORVEGICUS (NORWAY RAT)	GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2	A, B	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	492	Chemie (HOH)

Sequence modifications

A, B: 429 - 544 (UniProt: P42260)

PDB	External Database	Details
Gly 428	-	expression tag
Pro 807	-	expression tag
Arg 808	-	expression tag

A, B: 667 - 806 (UniProt: P42260)

PDB	External Database	Details
Gly 555	-	linker
Thr 566	-	linker
Lys 770	Met 770	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59247.9
Non-Polymers*	Number of molecules	5
	Total formula weight	375.7
All*	Total formula weight	59623.5

*Water molecules are not included.