2XXU
Crystal structure of the GluK2 (GluR6) M770K LBD dimer in complex with glutamate
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 900 |
| Chain | Residue |
| A | TYR488 |
| A | HOH2069 |
| A | HOH2126 |
| A | HOH2190 |
| A | HOH2258 |
| A | PRO516 |
| A | LEU517 |
| A | ALA518 |
| A | ARG523 |
| A | GLY688 |
| A | ALA689 |
| A | THR690 |
| A | GLU738 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU B 900 |
| Chain | Residue |
| B | TYR488 |
| B | PRO516 |
| B | LEU517 |
| B | ALA518 |
| B | ARG523 |
| B | GLY688 |
| B | ALA689 |
| B | THR690 |
| B | GLU738 |
| B | HOH2080 |
| B | HOH2127 |
| B | HOH2168 |
| B | HOH2234 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 901 |
| Chain | Residue |
| A | LYS531 |
| A | ARG775 |
| A | HOH2235 |
| B | LYS531 |
| B | ARG775 |
| B | HOH2207 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 902 |
| Chain | Residue |
| A | GLU524 |
| A | ILE527 |
| A | ASP528 |
| A | LYS770 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 902 |
| Chain | Residue |
| B | GLU524 |
| B | ILE527 |
| B | ASP528 |
| B | LYS770 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17115050","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S50","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15677325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8163463","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
