2XXB
Penta-mutant of Thermus thermophilus lactate dehydrogenase, complex with AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | L-LACTATE DEHYDROGENASE | polymer | 310 | 32599.4 | 2 | UniProt (Q5SJA1) Pfam (PF00056) Pfam (PF02866) | THERMUS THERMOPHILUS | L-LDH |
| 2 | C, D (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 331 (UniProt: Q5SJA1)
| PDB | External Database | Details |
|---|---|---|
| Trp 79 | Arg 58 | engineered mutation |
| Ala 151 | Arg 128 | engineered mutation |
| Ala 279 | Glu 260 | engineered mutation |
| Ala 299 | Glu 279 | engineered mutation |
| Ala 313 | Glu 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65198.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 694.4 | |
| All* | Total formula weight | 65893.2 |
